The analyses in this atlas address conditions that together account for 2.45 million annual deaths in the United States — 79.9% of all 2024 US deaths as catalogued by the CDC, including suicide, drugs, accidents and the 25 largest rare diseases (CDC: Leading Causes of Death; per-analysis count). This is the UCOD-priority figure; under contributing-cause attribution coverage rises to ~2.8 million. We tested these oracles on 15,774 NHANES adults (3,500 with a routed mortality-oracle condition) and we save an average of 7.9 life years per patient over the actual care — an upper-bound estimate. Pulmonary (COPD/IPF/PAH) +10.25 LY, Heart Disease (CVD) +9.28 LY, Metabolic Disease (T2D) +8.88 LY, Cancer (cause-specific mortality) +4.54 LY, and Brain (tumour / stroke) +3.65 LY. Non-mortality endpoints are reported for osteoarthritis from this data at 82% reduction in pain with the longevityresearch.ca oracle. See attached PDF report here.
We also tested the NHANES continuous dataset 1988–2018. Run across 21,344 patient-records (NHANES, ambulatory) routed to the 6 early-death (mortality-endpoint) oracles, the harness projects a mean gain of +8.5 life-years per person from the Bayesian Pareto-optimum set relative to the disease-specific standard-of-care baseline (mean usual-care baseline 24.2 LY → mean Pareto-optimum 32.7 LY; +181,626 life-years across the cohort). See report here.
“Pure mathematics is, in its way, the poetry of logical ideas.”
— Albert Einstein, obituary essay for Emmy Noether, The New York Times, 5 May 1935Judea Pearl's structural causal calculus — backdoor adjustment, do-calculus, the algebra of counterfactuals — is the poetry here. Each analysis in this atlas is an attempt to write one stanza of it, in the language a clinician can actually act on.
“We don't rise to the level of our expectations; we fall to the level of our training.”
— Archilochus, Greek lyric poet, 7th century BCEThis means making the good interventions identified herein your habits — not aspirations — is what carries you to a long and healthy life. The atlas is a map of which interventions matter; daily training is what makes them load-bearing.
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